SEATTLE (AP) — Sherman Alexie, one of the country's most prominent authors, issued an apology Wednesday amid multiple allegations of sexual misconduct.

"Over the years, I have done things that have harmed other people, including those I love most deeply," Alexie said in a statement released to The Seattle Times late Wednesday. "To those whom I have hurt, I genuinely apologize. I am so sorry."

Allegations against Alexie have been vague, referring to unwanted advances and inappropriate remarks and to threats against fellow American Indians. They appear to have first appeared publicly in anonymou...