TOPEKA, Kan. (AP) — Authorities said Wednesday that they've dismantled a major drug-trafficking operation in northeast Kansas responsible for a college student's fatal overdose in 2017, resulting in criminal charges against more than 50 people.

Federal and local officials said they've been investigating trafficking in heroin, methamphetamines, the powerful opioid fentanyl and other drugs in the Manhattan area for three years. They said some of the defendants now facing charges are former Chicago residents and obtained illegal drugs largely from Chicago.

A federal grand jury issued 13 indictmen...