Iowa State (5-3, 3-2 Big 12) at No. 9 Oklahoma (7-1, 4-1, No. 9 CFP), Saturday at 8 p.m. EST (FOX).

Line: Oklahoma by 14 1/2

Series record: Oklahoma leads 75-6-2.

WHAT'S AT STAKE?

Oklahoma likely will need to win out to keep its College Football Playoff hopes alive. The Sooners also need a victory to improve their chances of winning a fifth consecutive Big 12 title. Iowa State has hopes of reaching the conference championship game for the first time. Beating Oklahoma and muddying the race behind Big 12 leader Baylor would certainly increase the Cyclones' chances of getting there.

KEY MATCHUP

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