AUSTIN, Texas (AP) — George P. Bush on Wednesday launched his next political move: a run for Texas attorney general in 2022 that puts the scion of a Republican dynasty against a GOP incumbent shadowed by securities fraud charges and an FBI investigation.

Bush, who has served as Texas' land commissioner since 2015, is the son of former Florida Gov. Jeb Bush and the nephew and grandson of two former presidents. He is the last of the Bush family still in public office — and was the first to break with them over supporting former President Donald Trump, who has mocked the family that was once the...