OROVADA, Nevada (AP) — Just 45 miles (72 kilometers) from the Fort McDermitt Indian Reservation where Daranda Hinkey and her family corral horses and cows, a centerpiece of President Joe Biden's clean energy plan is taking shape: construction of one of the largest lithium mines in the world.

As heavy trucks dig up the earth in this remote, windswept region of Nevada to extract the silvery-white metal used in electric-vehicle batteries, the $2.2 billion project is fueling a backlash. "No Lithium. No mine!" proclaims a large hand-painted sign in Hinkey's front yard.

The Biden administration says...